Lieneke Janssen

Janssen-Lieneke

Post­doc­tor­al researcher

Max Planck Insti­tute for Human Cog­ni­tive & Brain Sciences
Stephanstraße 1A
04103 Leipzig
Germany

        

Profile

Lieneke com­plet­ed an under­grad­u­ate Bachelor’s degree in psy­chobi­ol­o­gy and a cog­ni­tive neu­ro­science research mas­ter in the Nether­lands. As a research assis­tant, she stud­ied the links between brain dopamine and gam­bling behav­ior. Lieneke com­plet­ed her PhD at the Don­ders Insti­tute, which focused on ‘Break­ing bad habits’, by inves­ti­gat­ing the effects of phar­ma­co­log­i­cal and behav­ioral inter­ven­tions on fron­tos­tri­atal pro­cess­ing. Since April 2017, Lieneke is work­ing as a post­doc­tor­al researcher in the O’Brain Project, where she stud­ies the role of dopamine and hemi­spher­ic asym­me­try in obesity.

Curriculum Vitae

2017— Post­doc­tor­al Researcher, IFB Adi­pos­i­ty­Dis­eases, Leipzig Uni­ver­si­ty – Med­ical Cen­ter, and guest researcher at the Max Planck Insti­tute for Human Cog­ni­tive and Brain Sci­ences, Junior Research Group “Deci­sion-mak­ing in Obe­si­ty” (Dr. Annette Horstmann).
2012–2016 PhD can­di­date, Don­ders Insti­tute, Rad­boud Uni­ver­si­ty, Nijmegen, the Nether­lands (Prof. Dr. Roshan Cools & Dr. Esther Aarts). The­sis: Break­ing Bad Habits — A med­i­ta­tion on the neu­rocog­ni­tive mech­a­nisms of com­pul­sive behavior.
2011–2012 Research Assis­tant, Don­ders Insti­tute, Rad­boud Uni­ver­si­ty, Nijmegen, the Nether­lands (Prof. Dr. Roshan Cools & Dr. Guil­laume Sescousse). Top­ic: Gam­bling and dopamine – A phar­ma­co­log­i­cal fMRI study.
2009–2011 Mas­ter degree in Cog­ni­tive Neu­ro­science (cum laude), Rad­boud Uni­ver­si­ty, Nijmegen, the Nether­lands. The­sis: State-depen­dent pro­cess­ing of tac­tile stim­uli in rat bar­rel cortex. 
2006–2009 Bach­e­lor degree in Psy­chobi­ol­o­gy (cum laude), Uni­ver­si­ty of Ams­ter­dam, Ams­ter­dam, the Nether­lands. The­sis: On motor imagery. 

Publications

Most Recent

Janssen, L., Duif, I., Speck­ens, A. E. M., van Loon, I., Weg­man, J., de Vries, J. H. M., Cools, R., & Aarts, E. (2023). The effects of an 8‑week mind­ful eat­ing inter­ven­tion on antic­i­pa­to­ry reward respons­es in stria­tum and mid­brain. Fron­tiers in Nutri­tion, 10: 1115727. doi:10.3389/fnut.2023.1115727.
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Schlögl, H., Janssen, L., Fasshauer, M., Miehle, K., Vill­ringer, A., Stumvoll, M., & Mueller, K. (2023). Reward pro­cess­ing dur­ing mon­e­tary incen­tive delay task after lep­tin sub­sti­tu­tion in lipody­s­tro­phy — An fMRI case series. Jour­nal of the Endocrine Soci­ety, 7(6): bvad052. doi:10.1210/jendso/bvad052.
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Janssen, L., & Horstmann, A. (2022). Mol­e­c­u­lar imag­ing of cen­tral dopamine in obe­si­ty: A qual­i­ta­tive review across sub­strates and radio­trac­ers. Brain Sci­ences, 12(4): 486. doi:10.3390/brainsci12040486.
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Janssen, L., Mah­n­er, F. P., Schla­gen­hauf, F., Deser­no, L., & Horstmann, A. (2020). Reliance on mod­el-based and mod­el-free con­trol in obe­si­ty. Sci­en­tif­ic Reports, 10(1): 22433. doi:10.1038/s41598-020–79929‑0.
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Hart­mann, H., Pauli, L., Janssen, L., Huhn, S., Ceglarek, U., & Horstmann, A. (2020). Pre­lim­i­nary evi­dence for an asso­ci­a­tion between intake of high-fat high-sugar diet, vari­a­tions in periph­er­al dopamine pre­cur­sor avail­abil­i­ty and dopamine-dependent cog­ni­tion in humans. Jour­nal of Neuroendocrinology, 32(12): e12917. doi:10.1111/jne.12917.
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2020

Janssen, L., Mah­n­er, F. P., Schla­gen­hauf, F., Deser­no, L., & Horstmann, A. (2020). Reliance on mod­el-based and mod­el-free con­trol in obe­si­ty. Sci­en­tif­ic Reports, 10(1): 22433. doi:10.1038/s41598-020–79929‑0.
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Hart­mann, H., Pauli, L., Janssen, L., Huhn, S., Ceglarek, U., & Horstmann, A. (2020). Pre­lim­i­nary evi­dence for an asso­ci­a­tion between intake of high-fat high-sugar diet, vari­a­tions in periph­er­al dopamine pre­cur­sor avail­abil­i­ty and dopamine-dependent cog­ni­tion in humans. Jour­nal of Neuroendocrinology, 32(12): e12917. doi:10.1111/jne.12917.
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Morys, F., Janssen, L., Ces­naite, E., Bey­er, F., Gar­cia-Gar­cia, I., Kum­ral, D., Liem, F., Mehl, N., Mahjoory, K., Schrimpf, A., Gae­bler, M., Mar­gulies, D. S., Vill­ringer, A., Neu­mann, J., Nikulin, V. V., & Horstmann, A. (2020). Hemi­spher­ic asym­me­tries in rest­ing-state EEG and fMRI are relat­ed to approach and avoid­ance behav­iour, but not to eat­ing behav­iour or BMI. Human Brain Map­ping, 41(5), 1136–1156. doi:10.1002/hbm.24864.
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2019

Janssen, L., Her­zog, N., Walt­mann, M., Breuer, N., Wiencke, K., Rausch, F., Hart­mann, H., Poes­sel, M., & Horstmann, A. (2019). Lost in trans­la­tion?: On the need for con­ver­gence in ani­mal and human stud­ies on the role of dopamine in diet-induced obe­si­ty. Cur­rent Addic­tion Reports, 6(3), 229–257. doi:10.1007/s40429-019–00268‑w.
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2018

van Holst, R. J., Janssen, L., van Mier­lo, P., Lam­mers, G. J., Cools, R., Overeem, S., & Aarts, E. (2018). Enhanced food-relat­ed respons­es in the ven­tral medi­al pre­frontal cor­tex in nar­colep­sy type 1. Sci­en­tif­ic Reports, 8: 16391. doi:10.1038/s41598-018–34647‑6.
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van Holst, R. J., Sescousse, G., Janssen, L., Janssen, M., Berry, A. S., Jagust, W. J., & Cools, R. (2018). Increased stri­atal dopamine syn­the­sis capac­i­ty in gam­bling addic­tion. Bio­log­i­cal Psychiatry, 83(12), 1036–1043. doi:10.1016/j.biopsych.2017.06.010.
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Sescousse, G., Ligneul, R., van Holst, R. J., Janssen, L., de Boer, F., Janssen, M., Berry, A. S., Jagust, W. J., & Cools, R. (2018). Spon­ta­neous eye blink rate and dopamine syn­the­sis capac­i­ty: Pre­lim­i­nary evi­dence for an absence of pos­i­tive cor­re­la­tion. Euro­pean Jour­nal of Neu­ro­science, 47(9), 1081–1086. doi:10.1111/ejn.13895.
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Janssen, L., Duif, I., van Loon, I., de Vries, J. H. M., Speck­ens, A. E. M., Cools, R., & Aarts, E. (2018). Greater mind­ful eat­ing prac­tice is asso­ci­at­ed with bet­ter rever­sal learn­ing. Sci­en­tif­ic Reports, 8: 5702 (2018). doi:10.1038/s41598-018–24001‑1.
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Ojala, K. E., Janssen, L., Hashe­mi, M. M., Tim­mer, M. H. M., Geurts, D. E. M., ter Huurne, N. P., Cools, R., & Sescousse, G. (2018). Dopamin­er­gic drug effects on prob­a­bil­i­ty weight­ing dur­ing risky deci­sion mak­ing. eNeu­ro, 5(2): e0330-18.2018. doi:10.1523/ENEURO.0330–18.2018.
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2017

Janssen, L., Duif, I., van Loon, I., Weg­man, J., de Vries, J. H. M., Cools, R., & Aarts, E. (2017). Loss of lat­er­al pre­frontal cor­tex con­trol in food-direct­ed atten­tion and goal-direct­ed food choice in obesity. Neu­roIm­age, 146, 148–156. doi:10.1016/j.neuroimage.2016.11.015.
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2016

Sescousse, G., Janssen, L., Hashe­mi, M., Tim­mer, M. H. M., Guerts, D. E. M., ter Huurne, N. P., Clark, L., & Cools, R. (2016). Ampli­fied stri­atal respons­es to near-miss out­comes in patho­log­i­cal gam­blers. Neu­ropsy­chophar­ma­col­o­gy, 41(10), 2614–2623. doi:10.1038/npp.2016.43.
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2015

Janssen, L., Sescousse, G., Hashe­mi, M. M., Tim­mer, M. H. M., ter Huurne, N. P., Geurts, D. E. M., & Cools, R. (2015). Abnor­mal mod­u­la­tion of reward ver­sus pun­ish­ment learn­ing by a dopamine D2-recep­tor antag­o­nist in patho­log­i­cal gam­blers. Psy­chophar­ma­col­o­gy, 232(18), 3345–3353. doi:10.1007/s00213-015‑3986‑y.
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2014 and before

ter Horst, A. C., Jongs­ma, M. L., Janssen, L., van Lier, R., & Steen­ber­gen, B. (2012). Dif­fer­ent men­tal rota­tion strate­gies reflect­ed in the rota­tion relat­ed neg­a­tiv­i­ty. Psychophysiology, 49(4), 566–573. doi:10.1111/j.1469–8986.2011.01322.x.
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Rikkert, M. G. M. O., Tona, K. D., Janssen, L., Burns, A., Lobo, A., Robert, P., Sar­to­rius, N., Stoppe, G., & Walde­mar, G. (2011). Valid­i­ty, reli­a­bil­i­ty, and fea­si­bil­i­ty of clin­i­cal stag­ing scales in demen­tia. Amer­i­can Jour­nal of Alzheimer’s Dis­ease and oth­er Demen­tias, 26(5), 357–365. doi:10.1177/1533317511418954.
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