Lieneke Janssen


Post­doc­tor­al researcher

Max Planck Insti­tute for Human Cog­ni­tive & Brain Sci­ences
Stephanstraße 1A
04103 Leipzig


Lieneke com­plet­ed an under­grad­u­ate Bachelor’s degree in psy­chobi­ol­o­gy and a cog­ni­tive neu­ro­science research mas­ter in the Nether­lands. As a research assis­tant, she stud­ied the links between brain dopamine and gam­bling behav­ior. Lieneke com­plet­ed her PhD at the Don­ders Insti­tute, which focused on ‘Break­ing bad habits’, by inves­ti­gat­ing the effects of phar­ma­co­log­i­cal and behav­ioral inter­ven­tions on fron­tos­tri­atal pro­cess­ing. Since April 2017, Lieneke is work­ing as a post­doc­tor­al researcher in the O’Brain Project, where she stud­ies the role of dopamine and hemi­spher­ic asym­me­try in obe­si­ty.

2017— Post­doc­tor­al Researcher, IFB Adi­pos­i­ty­Dis­eases, Leipzig Uni­ver­si­ty – Med­ical Cen­ter, and guest researcher at the Max Planck Insti­tute for Human Cog­ni­tive and Brain Sci­ences, Junior Research Group “Deci­sion-mak­ing in Obe­si­ty” (Dr. Annette Horstmann).
2012–2016 PhD can­di­date, Don­ders Insti­tute, Rad­boud Uni­ver­si­ty, Nijmegen, the Nether­lands (Prof. Dr. Roshan Cools & Dr. Esther Aarts). The­sis: Break­ing Bad Habits — A med­i­ta­tion on the neu­rocog­ni­tive mech­a­nisms of com­pul­sive behav­ior.
2011–2012 Research Assis­tant, Don­ders Insti­tute, Rad­boud Uni­ver­si­ty, Nijmegen, the Nether­lands (Prof. Dr. Roshan Cools & Dr. Guil­laume Sescousse). Top­ic: Gam­bling and dopamine – A phar­ma­co­log­i­cal fMRI study.
2009–2011 Mas­ter degree in Cog­ni­tive Neu­ro­science (cum laude), Rad­boud Uni­ver­si­ty, Nijmegen, the Nether­lands. The­sis: State-depen­dent pro­cess­ing of tac­tile stim­uli in rat bar­rel cor­tex.
2006–2009 Bach­e­lor degree in Psy­chobi­ol­o­gy (cum laude), Uni­ver­si­ty of Ams­ter­dam, Ams­ter­dam, the Nether­lands. The­sis: On motor imagery.


van Holst, R. J., Sescousse, G., Janssen, L., Janssen, M., Berry, A. S., Jagust, W. J., & Cools, R. (2018). Increased stri­atal dopamine syn­the­sis capac­i­ty in gam­bling addic­tion. Bio­log­i­cal Psy­chi­a­try, 83(12), 1036–1043. doi:10.1016/j.biopsych.2017.06.010.

Sescousse, G., Ligneul, R., van Holst, R. J., Janssen, L., de Boer, F., Janssen, M., Berry, A. S., Jagust, W. J., & Cools, R. (2018). Spon­ta­neous eye blink rate and dopamine syn­the­sis capac­i­ty: Pre­lim­i­nary evi­dence for an absence of pos­i­tive cor­re­la­tion. Euro­pean Jour­nal of Neu­ro­science, 47(9), 1081–1086. doi:10.1111/ejn.13895.
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Janssen, L., Duif, I., van Loon, I., de Vries, J. H. M., Speck­ens, A. E. M., Cools, R., & Aarts, E. (2018). Greater mind­ful eat­ing prac­tice is asso­ci­at­ed with bet­ter rever­sal learn­ing. Sci­en­tif­ic Reports, 8: 5702 (2018). doi:10.1038/s41598-018–24001-1.
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Janssen, L., Duif, I., van Loon, I., Weg­man, J., de Vries, J. H. M., Cools, R., & Aarts, E. (2017). Loss of lat­er­al pre­frontal cor­tex con­trol in food-direct­ed atten­tion and goal-direct­ed food choice in obe­si­ty. Neu­roIm­age, 146, 148–156. doi:10.1016/j.neuroimage.2016.11.015.

Sescousse, G., Janssen, L., Hashe­mi, M., Tim­mer, M. H. M., Guerts, D. E. M., ter Huurne, N. P., Clark, L., & Cools, R. (2016). Ampli­fied stri­atal respons­es to near-miss out­comes in patho­log­i­cal gam­blers. Neu­ropsy­chophar­ma­col­o­gy, 41(10), 2614–2623. doi:10.1038/npp.2016.43.

Janssen, L., Sescousse, G., Hashe­mi, M. M., Tim­mer, M. H. M., ter Huurne, N. P., Geurts, D. E. M., & Cools, R. (2015). Abnor­mal mod­u­la­tion of reward ver­sus pun­ish­ment learn­ing by a dopamine D2-recep­tor antag­o­nist in patho­log­i­cal gam­blers. Psy­chophar­ma­col­o­gy, 232(18), 3345–3353. doi:10.1007/s00213-015‑3986-y.
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ter Horst, A. C., Jongs­ma, M. L., Janssen, L., van Lier, R., & Steen­ber­gen, B. (2012). Dif­fer­ent men­tal rota­tion strate­gies reflect­ed in the rota­tion relat­ed neg­a­tiv­i­ty. Psy­chophys­i­ol­o­gy, 49(4), 566–573. doi:10.1111/j.1469–8986.2011.01322.x.

Rikkert, M. G. M. O., Tona, K. D., Janssen, L., Burns, A., Lobo, A., Robert, P., Sar­to­rius, N., Stoppe, G., & Walde­mar, G. (2011). Valid­i­ty, reli­a­bil­i­ty, and fea­si­bil­i­ty of clin­i­cal stag­ing scales in demen­tia. Amer­i­can Jour­nal of Alzheimer’s Dis­ease and oth­er Demen­tias, 26(5), 357–365. doi:10.1177/1533317511418954.