The University of Helsinki celebrates 386 years !!!
The University of Helsinki marks its 386th anniversary with a festive celebration. 🎉🎊
Welcome to the
O'BRAIN Lab
At O'Brain Lab, we investigate the neural mechanisms underlying decision-making, eating behavior, and obesity using advanced neuroimaging and computational neuroscience approaches.
The brain shapes what and how we eat. Yet in the same food environment, some people develop unhealthy eating patterns while others do not - and many struggle to stick to their dietary goals. Our lab studies how brain processes like learning, decision-making, and perception influence eating behaviour. Using cutting-edge neuroscience methods, we aim to uncover why eating goes wrong - and how this knowledge can inform interventions for conditions such as obesity that truly work.
Our Research
What We Investigate
Our research aims to understand the neural and cognitive mechanisms underlying eating behavior and obesity
Neural Mechanisms of Decision-Making
We investigate how the brain processes food-related decisions and how these mechanisms differ in individuals with obesity.
Eating Behavior & Self-Control
Understanding why dietary goals are difficult to maintain and how brain function relates to eating behaviors.
Computational Neuroscience
Using advanced computational models to understand cognitive processes underlying food choice and consumption.
Neuroimaging & Brain Plasticity
Employing fMRI, EEG, and other techniques to study brain structure, function, and plasticity related to eating behavior.
Meet the Lab
Our Team
Our interdisciplinary team combines expertise in neuroscience, psychology, nutrition, and computational methods
Our Research
Publications
113 publications in leading journals
Salivary extracellular vesicle-derived microRNAs are related to variances in parameters of obesity, taste and eating behaviour
Kristin Röhrborn, Anne Hoffmann, Andrea Lorenz, Peter Kovacs, Tobias Hagemann, Paul Czechowski, Maria Sehm, Annette Horstmann, Michael Stumvoll, Matthias Blüher, Imke Schamarek, Kerstin Rohde-Zimmermann
Molecular Metabolism (2025)
DOI: 10.1016/j.molmet.2025.102265 →FinnFoodPics: A database of Finnish snack foods for investigating modern eating behaviors
Arsene Kanyamibwa, Hendrik Hartmann, Daniel Fängström, William Vikatmaa, Beyza Pocan, Emily E. Perszyk, Xue S. Davis, Artemii Nikitin, Patrik Wikman, Tiina Pellinen, Niina E. Kaartinen, Ursula Schwab, Annette Horstmann
Food Quality and Preference (2025)
DOI: 10.1016/j.foodqual.2025.105512 →Ultra-processed food consumption affects structural integrity of feeding-related brain regions independent of and via adiposity
Filip Morys, Arsene Kanyamibwa, Daniel Fängström, Max Tweedale, Alexandre Pastor-Bernier, Houman Azizi, Lang Liu, Annette Horstmann, Alain Dagher
npj Metabolic Health and Disease (2025)
DOI: 10.1038/s44324-025-00056-3 →Neurocomputational Mechanisms Underlying Differential Reinforcement Learning From Wins and Losses in Obesity With and Without Binge Eating
Maria Waltmann, Nadine Herzog, Andrea M.F. Reiter, Arno Villringer, Annette Horstmann, Lorenz Deserno
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging (2024)
DOI: 10.1016/j.bpsc.2024.06.002 →Decrease in decision noise from adolescence into adulthood mediates an increase in more sophisticated choice behaviors and performance gain
Vanessa Scholz, Maria Waltmann, Nadine Herzog, Annette Horstmann, Lorenz Deserno
PLOS Biology (2024)
DOI: 10.1371/journal.pbio.3002877 →Balancing excitation and inhibition: The role of neural network dynamics in working memory gating
Nadine Herzog, Elena Cesnaite, Paul Steinfath, Nikolai Kapralov, Sean J. Fallon, Vadim Nikulin, Arno Villringer, Lieneke K. Janssen, Annette Horstmann
Imaging Neuroscience (2024)
DOI: 10.1162/imag_a_00380 →Working memory gating in obesity is moderated by striatal dopaminergic gene variants
Nadine Herzog, Hendrik Hartmann, Lieneke Katharina Janssen, Arsene Kanyamibwa, Maria Waltmann, Peter Kovacs, Lorenz Deserno, Sean Fallon, Arno Villringer, Annette Horstmann
eLife (2024)
DOI: 10.7554/elife.93369.3 →Working memory gating in obesity: Insights from a case-control fMRI study
Nadine Herzog, Hendrik Hartmann, Lieneke K. Janssen, Maria Waltmann, Sean J. Fallon, Lorenz Deserno, Annette Horstmann
Appetite (2024)
DOI: 10.1016/j.appet.2023.107179 →Distinct adaptations of endocrine and cognitive functions may contribute to high variability in long-term weight loss outcome after bariatric surgery
Mathis Lammert, Evelyn Medawar, Hendrik Hartmann, Linda Grasser, Arne Dietrich, Wiebke Fenske, Annette Horstmann
Physiology & Behavior (2023)
DOI: 10.1016/j.physbeh.2023.114279 →A randomized‐controlled trial to evaluate the app‐based multimodal weight loss program <i>zanadio</i> for patients with obesity
Lena Roth, Madeleine Ordnung, Katarina Forkmann, Nora Mehl, Annette Horstmann
Obesity (2023)
DOI: 10.1002/oby.23744 →Self-reported intake of high-fat and high-sugar diet is not associated with cognitive stability and flexibility in healthy men
Hendrik Hartmann, Lieneke K. Janssen, Nadine Herzog, Filip Morys, Daniel Fängström, Sean J. Fallon, Annette Horstmann
Appetite (2023)
DOI: 10.1016/j.appet.2023.106477 →Diminished reinforcement sensitivity in adolescence is associated with enhanced response switching and reduced coding of choice probability in the medial frontal pole
Maria Waltmann, Nadine Herzog, Andrea M.F. Reiter, Arno Villringer, Annette Horstmann, Lorenz Deserno
Developmental Cognitive Neuroscience (2023)
DOI: 10.1016/j.dcn.2023.101226 →Cortical Grey Matter Mediates Increases in Model-Based Control and Learning from Positive Feedback from Adolescence to Adulthood
Vanessa Scholz, Maria Waltmann, Nadine Herzog, Andrea Reiter, Annette Horstmann, Lorenz Deserno
The Journal of Neuroscience (2023)
DOI: 10.1523/jneurosci.1418-22.2023 →Nutrient scoring for the DEGS1-FFQ – from food intake to nutrient intake
Ronja Thieleking, Lennard Schneidewind, Arsene Kanyamibwa, Hendrik Hartmann, Annette Horstmann, A. Veronica Witte, Evelyn Medawar
BMC Nutrition (2023)
DOI: 10.1186/s40795-022-00636-2 →Die Evaluation von zanadio – Einer digitalen Gesundheitsanwendung für Erwachsene mit Adipositas (#27)
Lena Roth, Madeleine Ordnung, Katarina Forkmann, Nora Mehl, Annette Horstmann
Adipositas - Ursachen, Folgeerkrankungen, Therapie (2022)
DOI: 10.1055/s-0042-1755692 →Metabolic Profile and Metabolite Analyses in Extreme Weight Responders to Gastric Bypass Surgery
Charlotte M. Fries, Sven-Bastiaan Haange, Ulrike Rolle-Kampczyk, Andreas Till, Mathis Lammert, Linda Grasser, Evelyn Medawar, Arne Dietrich, Annette Horstmann, Martin von Bergen, Wiebke K. Fenske
Metabolites (2022)
DOI: 10.3390/metabo12050417 →Molecular Imaging of Central Dopamine in Obesity: A Qualitative Review across Substrates and Radiotracers
Lieneke Katharina Janssen, Annette Horstmann
Brain Sciences (2022)
DOI: 10.3390/brainsci12040486 →Brain response to food odors is not associated with body mass index and obesity-related metabolic health measures
Maria Poessel, Filip Morys, Nora Breuer, Arno Villringer, Thomas Hummel, Annette Horstmann
Appetite (2022)
DOI: 10.1016/j.appet.2021.105774 →Feasibility and utility of amygdala neurofeedback
Noam Goldway, Itamar Jalon, Jackob N. Keynan, Lydia Hellrung, Annette Horstmann, Christian Paret, Talma Hendler
Neuroscience & Biobehavioral Reviews (2022)
DOI: 10.1016/j.neubiorev.2022.104694 →Gut microbiota link dietary fiber intake and short-chain fatty acid metabolism with eating behavior
Evelyn Medawar, Sven-Bastiaan Haange, Ulrike Rolle-Kampczyk, Beatrice Engelmann, Arne Dietrich, Ronja Thieleking, Charlotte Wiegank, Charlotte Fries, Annette Horstmann, Arno Villringer, Martin von Bergen, Wiebke Fenske, A. Veronica Witte
Translational Psychiatry (2021)
DOI: 10.1038/s41398-021-01620-3 →Loss of control over eating: A systematic review of task based research into impulsive and compulsive processes in binge eating
Maria Waltmann, Nadine Herzog, Annette Horstmann, Lorenz Deserno
Neuroscience & Biobehavioral Reviews (2021)
DOI: 10.1016/j.neubiorev.2021.07.016 →Increased Brain Reward Responsivity to Food‐Related Odors in Obesity
Pengfei Han, Clemens Roitzsch, Annette Horstmann, Maria Pössel, Thomas Hummel
Obesity (2021)
DOI: 10.1002/oby.23170 →Author Correction: Reliance on model-based and model-free control in obesity
Lieneke K. Janssen, Florian P. Mahner, Florian Schlagenhauf, Lorenz Deserno, Annette Horstmann
Scientific Reports (2021)
DOI: 10.1038/s41598-021-83028-z →46 Die wissenschaftliche Evaluierung von zanadio – einem ganzheitlichen, digitalen Behandlungsprogramm für Menschen mit Adipositas
Madeleine Ordnung, Annette Horstmann
Adipositas - Ursachen, Folgeerkrankungen, Therapie (2021)
DOI: 10.1055/s-0041-1735676 →Reliance on model-based and model-free control in obesity
Lieneke K. Janssen, Florian P. Mahner, Florian Schlagenhauf, Lorenz Deserno, Annette Horstmann
Scientific Reports (2020)
DOI: 10.1038/s41598-020-79929-0 →Preliminary evidence for an association between intake of high‐fat high‐sugar diet, variations in peripheral dopamine precursor availability and dopamine‐dependent cognition in humans
Hendrik Hartmann, Larissa K. Pauli, Lieneke K. Janssen, Sebastian Huhn, Uta Ceglarek, Annette Horstmann
Journal of Neuroendocrinology (2020)
DOI: 10.1111/jne.12917 →Dopamine release, diffusion and uptake: A computational model for synaptic and volume transmission
Kathleen Wiencke, Annette Horstmann, David Mathar, Arno Villringer, Jane Neumann
PLOS Computational Biology (2020)
DOI: 10.1371/journal.pcbi.1008410 →Reduced Olfactory Bulb Volume in Obesity and Its Relation to Metabolic Health Status
Maria Poessel, Nora Breuer, Akshita Joshi, André Pampel, Arno Villringer, Thomas Hummel, Annette Horstmann
Frontiers in Human Neuroscience (2020)
DOI: 10.3389/fnhum.2020.586998 →The Aetiology of Olfactory Dysfunction and Its Relationship to Diet Quality
Richard J. Stevenson, Mehmet K. Mahmut, Annette Horstmann, Thomas Hummel
Brain Sciences (2020)
DOI: 10.3390/brainsci10110769 →Insulin Resistance Is Associated with Reduced Food Odor Sensitivity across a Wide Range of Body Weights
Maria Poessel, Jessica Freiherr, Kathleen Wiencke, Arno Villringer, Annette Horstmann
Nutrients (2020)
DOI: 10.3390/nu12082201 →Automatic and Controlled Processing: Implications for Eating Behavior
Sophia Fürtjes, Joseph A. King, Caspar Goeke, Maria Seidel, Thomas Goschke, Annette Horstmann, Stefan Ehrlich
Nutrients (2020)
DOI: 10.3390/nu12041097 →Hemispheric asymmetries in resting‐state EEG and fMRI are related to approach and avoidance behaviour, but not to eating behaviour or BMI
Filip Morys, Lieneke K. Janssen, Elena Cesnaite, Frauke Beyer, Isabel Garcia‐Garcia, Jana Kube, Deniz Kumral, Franziskus Liem, Nora Mehl, Keyvan Mahjoory, Anne Schrimpf, Michael Gaebler, Daniel Margulies, Arno Villringer, Jane Neumann, Vadim V. Nikulin, Annette Horstmann
Human Brain Mapping (2019)
DOI: 10.1002/hbm.24864 →Rapid Assessment of Olfactory Sensitivity Using the “Sniffin’ Sticks”
Maria Pössel, Jessica Freiherr, Annette Horstmann
Chemosensory Perception (2019)
DOI: 10.1007/s12078-019-09261-z →Characterizing impulsivity and resting‐state functional connectivity in normal‐weight binge eaters
Rossella Oliva, Filip Morys, Annette Horstmann, Umberto Castiello, Chiara Begliomini
International Journal of Eating Disorders (2019)
DOI: 10.1002/eat.23212 →Liking and left amygdala activity during food versus nonfood processing are modulated by emotional context
Isabel García-García, Jana Kube, Filip Morys, Anne Schrimpf, Ahmad S. Kanaan, Michael Gaebler, Arno Villringer, Alain Dagher, Annette Horstmann, Jane Neumann
Cognitive, Affective, & Behavioral Neuroscience (2019)
DOI: 10.3758/s13415-019-00754-8 →Lost in Translation? On the Need for Convergence in Animal and Human Studies on the Role of Dopamine in Diet-Induced Obesity
Lieneke K. Janssen, Nadine Herzog, Maria Waltmann, Nora Breuer, Kathleen Wiencke, Franziska Rausch, Hendrik Hartmann, Maria Poessel, Annette Horstmann
Current Addiction Reports (2019)
DOI: 10.1007/s40429-019-00268-w →(Epi)genetic regulation of CRTC1 in human eating behaviour and fat distribution
Kerstin Rohde, Maria Keller, Lars la Cour Poulsen, Torunn Rønningen, Michael Stumvoll, Anke Tönjes, Peter Kovacs, Annette Horstmann, Arno Villringer, Matthias Blüher, Yvonne Böttcher
eBioMedicine (2019)
DOI: 10.1016/j.ebiom.2019.05.050 →Appetitive Pavlovian-to-Instrumental Transfer in Participants with Normal-Weight and Obesity
Marie-Theres Meemken, Annette Horstmann
Nutrients (2019)
DOI: 10.3390/nu11051037 →The impulsive brain: Neural underpinnings of binge eating behavior in normal-weight adults
R. Oliva, F. Morys, A. Horstmann, U. Castiello, C. Begliomini
Appetite (2019)
DOI: 10.1016/j.appet.2018.12.043 →Unhealthy yet Avoidable—How Cognitive Bias Modification Alters Behavioral and Brain Responses to Food Cues in Individuals with Obesity
Nora Mehl, Filip Morys, Arno Villringer, Annette Horstmann
Nutrients (2019)
DOI: 10.3390/nu11040874 →A mind-brain-body dataset of MRI, EEG, cognition, emotion, and peripheral physiology in young and old adults
Anahit Babayan, Miray Erbey, Deniz Kumral, Janis D. Reinelt, Andrea M. F. Reiter, Josefin Röbbig, H. Lina Schaare, Marie Uhlig, Alfred Anwander, Pierre-Louis Bazin, Annette Horstmann, Leonie Lampe, Vadim V. Nikulin, Hadas Okon-Singer, Sven Preusser, André Pampel, Christiane S. Rohr, Julia Sacher, Angelika Thöne-Otto, Sabrina Trapp, Till Nierhaus, Denise Altmann, Katrin Arelin, Maria Blöchl, Edith Bongartz, Patric Breig, Elena Cesnaite, Sufang Chen, Roberto Cozatl, Saskia Czerwonatis, Gabriele Dambrauskaite, Maria Dreyer, Jessica Enders, Melina Engelhardt, Marie Michele Fischer, Norman Forschack, Johannes Golchert, Laura Golz, C. Alexandrina Guran, Susanna Hedrich, Nicole Hentschel, Daria I. Hoffmann, Julia M. Huntenburg, Rebecca Jost, Anna Kosatschek, Stella Kunzendorf, Hannah Lammers, Mark E. Lauckner, Keyvan Mahjoory, Ahmad S. Kanaan, Natacha Mendes, Ramona Menger, Enzo Morino, Karina Näthe, Jennifer Neubauer, Handan Noyan, Sabine Oligschläger, Patricia Panczyszyn-Trzewik, Dorothee Poehlchen, Nadine Putzke, Sabrina Roski, Marie-Catherine Schaller, Anja Schieferbein, Benito Schlaak, Robert Schmidt, Krzysztof J. Gorgolewski, Hanna Maria Schmidt, Anne Schrimpf, Sylvia Stasch, Maria Voss, Annett Wiedemann, Daniel S. Margulies, Michael Gaebler, Arno Villringer
Scientific Data (2019)
DOI: 10.1038/sdata.2018.308 →Correction to: Lost in Translation? On the Need for Convergence in Animal and Human Studies on the Role of Dopamine in Diet-Induced Obesity
Lieneke K. Janssen, Nadine Herzog, Maria Waltmann, Nora Breuer, Kathleen Wiencke, Franziska Rausch, Hendrik Hartmann, Maria Poessel, Annette Horstmann
Current Addiction Reports (2019)
DOI: 10.1007/s40429-019-00278-8 →Adipositas, Kognition und Entscheidungsverhalten
Annette Horstmann
Psychosoziale Aspekte der Adipositas-Chirurgie (2018)
DOI: 10.1007/978-3-662-57364-8_7 →Dorsolateral and medial prefrontal cortex mediate the influence of incidental priming on economic decision making in obesity
Filip Morys, Stefan Bode, Annette Horstmann
Scientific Reports (2018)
DOI: 10.1038/s41598-018-35834-1 →Keeping track of promised rewards: Obesity predicts enhanced flexibility when learning from observation
Marie T. Meemken, Jana Kube, Carolin Wickner, Annette Horstmann
Appetite (2018)
DOI: 10.1016/j.appet.2018.08.029 →Retraining automatic action tendencies in obesity
Nora Mehl, Lara Mueller-Wieland, David Mathar, Annette Horstmann
Physiology & Behavior (2018)
DOI: 10.1016/j.physbeh.2018.03.031 →Intermittent compared to continuous real-time fMRI neurofeedback boosts control over amygdala activation
Lydia Hellrung, Anja Dietrich, Maurice Hollmann, Burkhard Pleger, Christian Kalberlah, Elisabeth Roggenhofer, Arno Villringer, Annette Horstmann
NeuroImage (2018)
DOI: 10.1016/j.neuroimage.2017.10.031 →Altered monetary loss processing and reinforcement-based learning in individuals with obesity
Jana Kube, David Mathar, Annette Horstmann, Sonja A. Kotz, Arno Villringer, Jane Neumann
Brain Imaging and Behavior (2017)
DOI: 10.1007/s11682-017-9786-8 →Effects of psychological eating behaviour domains on the association between socio-economic status and BMI
Antje Löffler, Tobias Luck, Francisca S Then, Claudia Luck-Sikorski, Alexander Pabst, Peter Kovacs, Yvonne Böttcher, Jana Breitfeld, Anke Tönjes, Annette Horstmann, Markus Löffler, Christoph Engel, Joachim Thiery, Arno Villringer, Michael Stumvoll, Steffi G Riedel-Heller
Public Health Nutrition (2017)
DOI: 10.1017/s1368980017001653 →Failing to learn from negative prediction errors: Obesity is associated with alterations in a fundamental neural learning mechanism
David Mathar, Jane Neumann, Arno Villringer, Annette Horstmann
Cortex (2017)
DOI: 10.1016/j.cortex.2017.08.022 →It wasn't me; it was my brain – Obesity-associated characteristics of brain circuits governing decision-making
Annette Horstmann
Physiology & Behavior (2017)
DOI: 10.1016/j.physbeh.2017.04.001 →The role of dopamine in positive and negative prediction error utilization during incidental learning – Insights from Positron Emission Tomography, Parkinson's disease and Huntington's disease
David Mathar, Leonora Wilkinson, Anna K. Holl, Jane Neumann, Lorenz Deserno, Arno Villringer, Marjan Jahanshahi, Annette Horstmann
Cortex (2017)
DOI: 10.1016/j.cortex.2016.09.004 →Cause or consequence? Investigating attention bias and self-regulation skills in children at risk for obesity
Nora Mehl, Sarah Bergmann, Annette M. Klein, Moritz Daum, Kai von Klitzing, Annette Horstmann
Journal of Experimental Child Psychology (2017)
DOI: 10.1016/j.jecp.2016.11.003 →Parasympathetic cardio-regulation during social interactions in individuals with obesity—The influence of negative body image
Anne Schrimpf, Jana Kube, Jane Neumann, Annette Horstmann, Arno Villringer, Michael Gaebler
Cognitive, Affective, & Behavioral Neuroscience (2016)
DOI: 10.3758/s13415-016-0482-8 →Stopping at the sight of food – How gender and obesity impact on response inhibition
Christoph Mühlberg, David Mathar, Arno Villringer, Annette Horstmann, Jane Neumann
Appetite (2016)
DOI: 10.1016/j.appet.2016.08.121 →Parasympathetic cardio-regulation during social interactions in individuals with obesity-The influence of negative body image.
Schrimpf A, Kube J, Neumann J, Horstmann A, Villringer A, Gaebler M
(2016)
Random Projection for Fast and Efficient Multivariate Correlation Analysis of High-Dimensional Data: A New Approach
Claudia Grellmann, Jane Neumann, Sebastian Bitzer, Peter Kovacs, Anke Tönjes, Lars T. Westlye, Ole A. Andreassen, Michael Stumvoll, Arno Villringer, Annette Horstmann
Frontiers in Genetics (2016)
DOI: 10.3389/fgene.2016.00102 →Leptin substitution in patients with lipodystrophy: neural correlates for long-term success in the normalization of eating behavior.
Schlögl H, Müller K, Horstmann A, Miehle K, Püschel J, Villringer A, Pleger B, Stumvoll M, Fasshauer M
(2016)
Neural processing of negative emotional stimuli and the influence of age, sex and task-related characteristics
I. García-García, J. Kube, M. Gaebler, A. Horstmann, A. Villringer, J. Neumann
Neuroscience & Biobehavioral Reviews (2016)
DOI: 10.1016/j.neubiorev.2016.04.020 →Brain regulation of food craving: relationships with weight status and eating behavior
A Dietrich, M Hollmann, D Mathar, A Villringer, A Horstmann
International Journal of Obesity (2016)
DOI: 10.1038/ijo.2016.28 →Differential heart rate responses to social and monetary reinforcement in women with obesity
Jana Kube, Anne Schrimpf, Isabel García‐García, Arno Villringer, Jane Neumann, Annette Horstmann
Psychophysiology (2016)
DOI: 10.1111/psyp.12624 →Functional neuroimaging in obesity and the potential for development of novel treatments
Haiko Schlögl, Annette Horstmann, Arno Villringer, Michael Stumvoll
The Lancet Diabetes & Endocrinology (2016)
DOI: 10.1016/s2213-8587(15)00475-1 →Higher body mass index in older adults is associated with lower gray matter volume: implications for memory performance
Shahrzad Kharabian Masouleh, Katrin Arélin, Annette Horstmann, Leonie Lampe, Judy A. Kipping, Tobias Luck, Steffi G. Riedel-Heller, Matthias L. Schroeter, Michael Stumvoll, Arno Villringer, Anja Veronica Witte
Neurobiology of Aging (2016)
DOI: 10.1016/j.neurobiolaging.2015.12.020 →Is it Worth the Effort? Novel Insights into Obesity-Associated Alterations in Cost-Benefit Decision-Making
David Mathar, Annette Horstmann, Burkhard Pleger, Arno Villringer, Jane Neumann
Frontiers in Behavioral Neuroscience (2016)
DOI: 10.3389/fnbeh.2015.00360 →General Habit Propensity Relates to the Sensation Seeking Subdomain of Impulsivity But Not Obesity
Anja Dietrich, Sanne de Wit, Annette Horstmann
Frontiers in Behavioral Neuroscience (2016)
DOI: 10.3389/fnbeh.2016.00213 →Slips of Action and Sequential Decisions: A Cross-Validation Study of Tasks Assessing Habitual and Goal-Directed Action Control
Zsuzsika Sjoerds, Anja Dietrich, Lorenz Deserno, Sanne de Wit, Arno Villringer, Hans-Jochen Heinze, Florian Schlagenhauf, Annette Horstmann
Frontiers in Behavioral Neuroscience (2016)
DOI: 10.3389/fnbeh.2016.00234 →Lateral prefrontal model-based signatures are reduced in healthy individuals with high trait impulsivity
L Deserno, T Wilbertz, A Reiter, A Horstmann, J Neumann, A Villringer, H-J Heinze, F Schlagenhauf
Translational Psychiatry (2015)
DOI: 10.1038/tp.2015.139 →Incidental rewarding cues influence economic decisions in people with obesity
Jakob Simmank, Carsten Murawski, Stefan Bode, Annette Horstmann
Frontiers in Behavioral Neuroscience (2015)
DOI: 10.3389/fnbeh.2015.00278 →Functional network centrality in obesity: A resting-state and task fMRI study
Isabel García-García, María Ángeles Jurado, Maite Garolera, Idoia Marqués-Iturria, Annette Horstmann, Bàrbara Segura, Roser Pueyo, María José Sender-Palacios, Maria Vernet-Vernet, Arno Villringer, Carme Junqué, Daniel S. Margulies, Jane Neumann
Psychiatry Research: Neuroimaging (2015)
DOI: 10.1016/j.pscychresns.2015.05.017 →Age- and gender-specific norms for the German version of the Three-Factor Eating-Questionnaire (TFEQ)
Antje Löffler, Tobias Luck, Francisca S. Then, Melanie Luppa, Claudia Sikorski, Peter Kovacs, Anke Tönjes, Yvonne Böttcher, Jana Breitfeld, Annette Horstmann, Markus Löffler, Christoph Engel, Joachim Thiery, Michael Stumvoll, Steffi G. Riedel-Heller
Appetite (2015)
DOI: 10.1016/j.appet.2015.04.044 →Physical exercise in overweight to obese individuals induces metabolic- and neurotrophic-related structural brain plasticity
Karsten Mueller, Harald E. Möller, Annette Horstmann, Franziska Busse, Jöran Lepsien, Matthias Blüher, Michael Stumvoll, Arno Villringer, Burkhard Pleger
Frontiers in Human Neuroscience (2015)
DOI: 10.3389/fnhum.2015.00372 →Eating Behaviour in the General Population: An Analysis of the Factor Structure of the German Version of the Three-Factor-Eating-Questionnaire (TFEQ) and Its Association with the Body Mass Index
Antje Löffler, Tobias Luck, Francisca S. Then, Claudia Sikorski, Peter Kovacs, Yvonne Böttcher, Jana Breitfeld, Anke Tönjes, Annette Horstmann, Markus Löffler, Christoph Engel, Joachim Thiery, Arno Villringer, Michael Stumvoll, Steffi G. Riedel-Heller
PLOS ONE (2015)
DOI: 10.1371/journal.pone.0133977 →Argument for a non‐linear relationship between severity of human obesity and dopaminergic tone
A. Horstmann, W. K. Fenske, M. K. Hankir
Obesity Reviews (2015)
DOI: 10.1111/obr.12303 →Data from 617 Healthy Participants Performing the Iowa Gambling Task: A “Many Labs” Collaboration
Helen Steingroever, Daniel J. Fridberg, Annette Horstmann, Kimberly L. Kjome, Veena Kumari, Scott D. Lane, Tiago V. Maia, James L. McClelland, Thorsten Pachur, Preethi Premkumar, Julie C. Stout, Ruud Wetzels, Stacey Wood, Darrell A. Worthy, Eric-Jan Wagenmakers
Journal of Open Psychology Data (2015)
DOI: 10.5334/jopd.ak →Distinctive striatal dopamine signaling after dieting and gastric bypass
Mohammed K. Hankir, Hutan Ashrafian, Swen Hesse, Annette Horstmann, Wiebke K. Fenske
Trends in Endocrinology & Metabolism (2015)
DOI: 10.1016/j.tem.2015.03.005 →The Brain’s Got a Taste for Good Food
Annette Horstmann
Hedonic Eating (2015)
DOI: 10.1093/med/9780199330454.003.0003 →Flexible Adaptive Paradigms for fMRI Using a Novel Software Package ‘Brain Analysis in Real-Time’ (BART)
Lydia Hellrung, Maurice Hollmann, Oliver Zscheyge, Torsten Schlumm, Christian Kalberlah, Elisabeth Roggenhofer, Hadas Okon-Singer, Arno Villringer, Annette Horstmann
PLOS ONE (2015)
DOI: 10.1371/journal.pone.0118890 →Genetic variants in AKR1B10 associate with human eating behavior
Kerstin Rohde, Martin Federbusch, Annette Horstmann, Maria Keller, Arno Villringer, Michael Stumvoll, Anke Tönjes, Peter Kovacs, Yvonne Böttcher
BMC Genetics (2015)
DOI: 10.1186/s12863-015-0189-9 →Comparison of variants of canonical correlation analysis and partial least squares for combined analysis of MRI and genetic data
Claudia Grellmann, Sebastian Bitzer, Jane Neumann, Lars T. Westlye, Ole A. Andreassen, Arno Villringer, Annette Horstmann
NeuroImage (2015)
DOI: 10.1016/j.neuroimage.2014.12.025 →Slave to habit? Obesity is associated with decreased behavioural sensitivity to reward devaluation
Annette Horstmann, Anja Dietrich, David Mathar, Maria Pössel, Arno Villringer, Jane Neumann
Appetite (2015)
DOI: 10.1016/j.appet.2014.12.212 →Role of genetic variants in ADIPOQ in human eating behavior
Kerstin Rohde, Maria Keller, Annette Horstmann, Xuanshi Liu, Fabian Eichelmann, Michael Stumvoll, Arno Villringer, Peter Kovacs, Anke Tönjes, Yvonne Böttcher
Genes & Nutrition (2014)
DOI: 10.1007/s12263-014-0449-8 →Identifying neural correlates of memory and language disturbances in herpes simplex encephalitis: a voxel-based morphometry (VBM) study.
Frisch S, Thiel F, Marschhauser A, Villringer A, Horstmann A, Schroeter ML
(2014)
Reward processing in obesity, substance addiction and non‐substance addiction
I. García‐García, A. Horstmann, M. A. Jurado, M. Garolera, S. J. Chaudhry, D. S. Margulies, A. Villringer, J. Neumann
Obesity Reviews (2014)
DOI: 10.1111/obr.12221 →Response inhibition and its relation to multidimensional impulsivity.
Wilbertz T, Deserno L, Horstmann A, Neumann J, Villringer A, Heinze HJ, Boehler CN, Schlagenhauf F
(2014)
Body weight status, eating behavior, sensitivity to reward/punishment, and gender: relationships and interdependencies
Anja Dietrich, Martin Federbusch, Claudia Grellmann, Arno Villringer, Annette Horstmann
Frontiers in Psychology (2014)
DOI: 10.3389/fpsyg.2014.01073 →Identifying neural correlates of memory and language disturbances in herpes simplex encephalitis: a voxel-based morphometry (VBM) study
Stefan Frisch, Friederike Thiel, Anke Marschhauser, Arno Villringer, Annette Horstmann, Matthias L. Schroeter
Journal of Neurology (2014)
DOI: 10.1007/s00415-014-7604-4 →Obesity Associated Cerebral Gray and White Matter Alterations Are Interrelated in the Female Brain.
Mueller K, Horstmann A, Möller HE, Anwander A, Lepsien J, Schroeter ML, Villringer A, Pleger B
(2014)
Obesity Associated Cerebral Gray and White Matter Alterations Are Interrelated in the Female Brain
Karsten Mueller, Annette Horstmann, Harald E. Möller, Alfred Anwander, Jöran Lepsien, Matthias L. Schroeter, Arno Villringer, Burkhard Pleger
PLOS ONE (2014)
DOI: 10.1371/journal.pone.0114206 →Response inhibition and its relation to multidimensional impulsivity
Tilmann Wilbertz, Lorenz Deserno, Annette Horstmann, Jane Neumann, Arno Villringer, Hans-Jochen Heinze, Carsten N. Boehler, Florian Schlagenhauf
NeuroImage (2014)
DOI: 10.1016/j.neuroimage.2014.09.021 →Common Genetic Variation near MC4R Has a Sex-Specific Impact on Human Brain Structure and Eating Behavior
Annette Horstmann, Peter Kovacs, Stefan Kabisch, Yvonne Boettcher, Haiko Schloegl, Anke Tönjes, Michael Stumvoll, Burkhard Pleger, Arno Villringer
PLOS ONE (2013)
DOI: 10.1371/journal.pone.0074362 →The role of rs2237781 within<i>GRM8</i>in eating behavior
Marie‐Therese Gast, Anke Tönjes, Maria Keller, Annette Horstmann, Nanette Steinle, Markus Scholz, Ines Müller, Arno Villringer, Michael Stumvoll, Peter Kovacs, Yvonne Böttcher
Brain and Behavior (2013)
DOI: 10.1002/brb3.151 →Exenatide-Induced Reduction in Energy Intake Is Associated With Increase in Hypothalamic Connectivity
Haiko Schlögl, Stefan Kabisch, Annette Horstmann, Gabriele Lohmann, Karsten Müller, Jöran Lepsien, Franziska Busse-Voigt, Jürgen Kratzsch, Burkhard Pleger, Arno Villringer, Michael Stumvoll
Diabetes Care (2013)
DOI: 10.2337/dc12-1925 →Diagnostic imaging in obesity
Jürgen Machann, Annette Horstmann, Mark Born, Swen Hesse, Franz Wolfgang Hirsch
Best Practice & Research Clinical Endocrinology & Metabolism (2013)
DOI: 10.1016/j.beem.2013.02.003 →Performance of healthy participants on the Iowa Gambling Task.
Helen Steingroever, Ruud Wetzels, Annette Horstmann, Jane Neumann, Eric-Jan Wagenmakers
Psychological Assessment (2013)
DOI: 10.1037/a0029929 →Brain imaging in the context of food perception and eating
Maurice Hollmann, Burkhard Pleger, Arno Villringer, Annette Horstmann
Current Opinion in Lipidology (2013)
DOI: 10.1097/mol.0b013e32835b61a4 →Dissociating Memory Networks in Early Alzheimer’s Disease and Frontotemporal Lobar Degeneration - A Combined Study of Hypometabolism and Atrophy
Stefan Frisch, Juergen Dukart, Barbara Vogt, Annette Horstmann, Georg Becker, Arno Villringer, Henryk Barthel, Osama Sabri, Karsten Müller, Matthias L. Schroeter
PLOS ONE (2013)
DOI: 10.1371/journal.pone.0055251 →Corrigendum: Iowa gambling task: there is more to consider than long-term outcome. Using a linear equation model to disentangle the impact of outcome and frequency of gains and losses.
Horstmann A, Villringer A, Neumann J
(2013)
The role of the brain in obesity,Die rolle des gehirns bei adipositas
Horstmann, A., Villringer, A.
Neuroforum (2013)
Iowa Gambling Task: there is more to consider than long-term outcome. Using a linear equation model to disentangle the impact of outcome and frequency of gains and losses
Annette Horstmann
Frontiers in Neuroscience (2012)
DOI: 10.3389/fnins.2012.00061 →Neural correlates of the volitional regulation of the desire for food
M Hollmann, L Hellrung, B Pleger, H Schlögl, S Kabisch, M Stumvoll, A Villringer, A Horstmann
International Journal of Obesity (2011)
DOI: 10.1038/ijo.2011.125 →Peptide hormones regulating appetite—focus on neuroimaging studies in humans
Haiko Schloegl, Ruth Percik, Annette Horstmann, Arno Villringer, Michael Stumvoll
Diabetes/Metabolism Research and Reviews (2011)
DOI: 10.1002/dmrr.1154 →Combined Evaluation of FDG-PET and MRI Improves Detection and Differentiation of Dementia
Juergen Dukart, Karsten Mueller, Annette Horstmann, Henryk Barthel, Harald E. Möller, Arno Villringer, Osama Sabri, Matthias L. Schroeter
PLOS ONE (2011)
DOI: 10.1371/journal.pone.0018111 →Focal Retrograde Amnesia: Voxel-Based Morphometry Findings in a Case without MRI Lesions
Bernhard Sehm, Stefan Frisch, Angelika Thöne-Otto, Annette Horstmann, Arno Villringer, Hellmuth Obrig
PLOS ONE (2011)
DOI: 10.1371/journal.pone.0026538 →Obesity-Related Differences between Women and Men in Brain Structure and Goal-Directed Behavior
Annette Horstmann, Franziska P. Busse, David Mathar, Karsten Müller, Jöran Lepsien, Haiko Schlögl, Stefan Kabisch, Jürgen Kratzsch, Jane Neumann, Michael Stumvoll, Arno Villringer, Burkhard Pleger
Frontiers in Human Neuroscience (2011)
DOI: 10.3389/fnhum.2011.00058 →Sex-Dependent Influences of Obesity on Cerebral White Matter Investigated by Diffusion-Tensor Imaging
Karsten Mueller, Alfred Anwander, Harald E. Möller, Annette Horstmann, Jöran Lepsien, Franziska Busse, Siawoosh Mohammadi, Matthias L. Schroeter, Michael Stumvoll, Arno Villringer, Burkhard Pleger
PLOS ONE (2011)
DOI: 10.1371/journal.pone.0018544 →Multivariate information-theoretic measures reveal directed information structure and task relevant changes in fMRI connectivity
Joseph T. Lizier, Jakob Heinzle, Annette Horstmann, John-Dylan Haynes, Mikhail Prokopenko
Journal of Computational Neuroscience (2010)
DOI: 10.1007/s10827-010-0271-2 →Dynamic Properties of Human Brain Structure: Learning-Related Changes in Cortical Areas and Associated Fiber Connections
Marco Taubert, Bogdan Draganski, Alfred Anwander, Karsten Müller, Annette Horstmann, Arno Villringer, Patrick Ragert
The Journal of Neuroscience (2010)
DOI: 10.1523/jneurosci.2567-10.2010 →Resuscitating the heart but losing the brain: brain atrophy in the aftermath of cardiac arrest.
Authors not available
(2010)
Differential effects of global and cerebellar normalization on detection and differentiation of dementia in FDG-PET studies
Juergen Dukart, Karsten Mueller, Annette Horstmann, Barbara Vogt, Stefan Frisch, Henryk Barthel, Georg Becker, Harald E. Möller, Arno Villringer, Osama Sabri, Matthias L. Schroeter
NeuroImage (2010)
DOI: 10.1016/j.neuroimage.2009.09.017 →Eigenvector Centrality Mapping for Analyzing Connectivity Patterns in fMRI Data of the Human Brain
Gabriele Lohmann, Daniel S. Margulies, Annette Horstmann, Burkhard Pleger, Joeran Lepsien, Dirk Goldhahn, Haiko Schloegl, Michael Stumvoll, Arno Villringer, Robert Turner
PLOS ONE (2010)
DOI: 10.1371/journal.pone.0010232 →Resuscitating the heart but losing the brain
A. Horstmann, S. Frisch, R. T. Jentzsch, K. Müller, A. Villringer, M. L. Schroeter
Neurology (2010)
DOI: 10.1212/wnl.0b013e3181cbcd6f →Target selection in eye–hand coordination: Do we reach to where we look or do we look to where we reach?
Annette Horstmann, Klaus-Peter Hoffmann
Experimental Brain Research (2005)
DOI: 10.1007/s00221-005-0038-6 →Get Involved
Participate in Our Studies
We are recruiting participants for exciting research projects. Your participation helps advance our understanding of brain function and eating behavior.
LUMINA Project
Beyond the common symptoms induced by cancer treatments commonly experienced (e.g., nausea, fatigue…), some symptoms can persist even months after the end of their treatment. Many survivors have reported dizziness, difficulty in attention and concentration, or brief loss of memory. All of these relate to the brain and to what is called 'cognitive functions'. This project aims to explore how brain function is affected after breast cancer and how these changes impact survivors' daily lives compared to people without cancer.
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MARVEL Project
Beyond the simple act of choosing what to eat, our food decisions are influenced by how we perceive the value of different snacks and by the environment we are in when making these choices. This project seeks to understand how people evaluate common and familiar snack foods and how varying contexts might shape eating behavior. By studying these patterns, we aim to gain insights into how everyday food choices are formed and what factors guide them.
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EEEH Project
This project explores how personality traits, perceived everyday situations, and stress-related experiences interact to shape daily food choices in young adults.
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View all posts »Stay updated with our latest research findings, lab activities, and team achievements. Follow our news for insights into ongoing projects and recent publications.
Congrats to Dr. Nadine Herzog on her Thesis Defence!
Dr. Nadine Herzog (MD) defended her doctoral thesis at the University of Leipzig. Congratulations! 🎉🎊
Welcome to our new Erasmus + intern Lena Traser !!!
New Research Intern! 🎉🎊🥳
New grant received from Instrumentarium Science Foundation!
Doctoral researcher Arsene Kanyamibwa received a grant from Instrumentarium Science Foundation! 🎉🎊🥳
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